Some of the microbes that make carbon sequestration work. (credit: Andes Ag, Inc)

In 2022, humans emitted a staggering 36 gigatons of carbon dioxide into the atmosphere. Along with reducing emissions, removing carbon dioxide from the atmosphere is a key climate mitigation strategy. But Gonzalo Fuenzalida wasn’t looking to help solve climate change when he co-founded the company Andes .

“We started this company with the idea of using microbes to make the process of growing food more resilient,” says Fuenzalida. “We stumbled upon these microbes that have the ability to create minerals in the soil which contain carbon and that intrigued us.”

Fuenzalida, alongside his co-founder Tania Timmermann-Aranis, had an unconventional notion: They could harness the power of microbes residing in plant roots within the soil to remove carbon from the atmosphere. These naturally occurring microbes can be applied to the soil by blending them with pesticides or other soil treatments—they will strategically position themselves within the root structure of corn, wheat, and soy plants.

Enlarge / Whether the toilet lid is up or down doesn't make much difference in the spread of airborne bacterial and viral particles. (credit: Peter Dazeley )

File this one under "Studies We Wish Had Let Us Remain Ignorant." Scientists at the University of Arizona decided to investigate whether closing the toilet lid before flushing reduces cross-contamination of bathroom surfaces by airborne bacterial and viral particles via " toilet plumes ." The bad news is that putting a lid on it doesn't result in any substantial reduction in contamination, according to their recent paper published in the American Journal of Infection Control. The good news: Adding a disinfectant to the toilet bowl before flushing and using disinfectant dispensers in the tank significantly reduce cross-contamination.

Regarding toilet plumes, we're not just talking about large water droplets that splatter when a toilet is flushed. Even smaller droplets can form and be spread into the surrounding air, potentially carrying bacteria like E. coli or a virus (e.g., norovirus) if an infected person has previously used said toilet. Pathogens can linger in the bowl even after repeated flushes, just waiting for their chance to launch into the air and spread disease. That's because larger droplets, in particular, can settle on surfaces before they dry, while smaller ones travel further on natural air currents.

The first experiments examining whether toilet plumes contained contaminated particles were done in the 1950s, and the notion that disease could be spread this way was popularized in a 1975 study . In 2022, physicists and engineers at the University of Colorado, Boulder, managed to visualize toilet plumes of tiny airborne particles ejected from toilets during a flush using a combination of green lasers and cameras. It made for some pretty vivid video footage:

Here at Ars, we've covered versions of Doom running on everything from hacked printers to Windows' notepad.exe to a version running inside Doom itself . But these and the other many and varied examples of weird Doom platforms all lack the sheer biological oddness of a new model for displaying the game using a grid of E. coli bacteria.

MIT graduate student Lauren Ramlan outlines a method for creating the quixotic Doom display in "1-Bit Pixels Encoded in E. Coli for the Display of Interactive Digital Media," the final project for a Principles of Synthetic Biology class. Ramlan's project builds on earlier research describing how the DNA in E. coli bacteria can be used to encode full digital circuits and how the bacteria itself can be induced to fluoresce as a crude form of digital display.

The kind of cell grid that could hold a phosphorescent E. coli "display." (credit: Fisher Scientific )

Ramlan's paper doesn't go to the enormous trouble of actually encoding all of Doom to run in bacterial DNA, which the author describes as "a behemoth feat that I cannot even imagine approaching." Instead, the game runs on a standard computer, with isolated E. coli cells in a standard 32x48 microwell grid serving as a crude low-res display.

Enlarge / This Scanning Electron Microscope image depicts several clusters of aerobic Gram-negative, non-motile Acinetobacter baumannii bacteria under a magnification of 24,730x. Members of the genus Acinetobacter are nonmotile rods, 1-1.5µm in diameter, and 1.5-2.5µm in length, becoming spherical in shape while in their stationary phase of growth. This bacteria is oxidase-negative and therefore does not utilize oxygen for energy production. They also occur in pairs under magnification. Acinetobacter spp. are widely distributed in nature, and are normal flora on the skin. Some members of the genus are important because they are an emerging cause of hospital acquired pulmonary, i.e., pneumoniae, hemopathic, and wound infections. Because the organism has developed substantial antimicrobial resistance, treatment of infections attributed to A. baumannii has become increasingly difficult. The only drug that works on multi-resistant strains of A.baumannii is colistin which is a very toxic drug.

A new experimental antibiotic can handily knock off one of the world's most notoriously drug-resistant and deadly bacteria —in lab dishes and mice, at least. It does so with a never-before-seen method, cracking open an entirely new class of drugs that could yield more desperately needed new therapies for fighting drug-resistant infections.

The findings appeared this week in a pair of papers published in Nature, which lay out the extensive drug development work conducted by researchers at Harvard University and the Swiss-based pharmaceutical company Roche.

In an accompanying commentary, chemists Morgan Gugger and Paul Hergenrother of the University of Illinois at Urbana-Champaign discussed the findings with optimism, noting that it has been more than 50 years since the Food and Drug Administration has approved a new class of antibiotics against the category of bacteria the drug targets: Gram-negative bacteria. This category—which includes gut pathogens such as E. coli , Salmonella , Shigella , and the bacteria that cause chlamydia, the bubonic plague, gonorrhea, whooping cough, cholera, and typhoid, to name a few—is extraordinarily challenging to kill because it's defined by having a complex membrane structure that blocks most drugs, and it's good at accumulating other drug-resistance strategies

Enlarge (credit: Koval Nadiya )

There is no questioning our ongoing love affair with cheese. From pizza and pasta to that decadent slice of cheesecake, we can’t get enough. But the dairy industry that produces cheese has had a negative impact on our climate that is not exactly appetizing.

While plant-based alternatives to cheese are easier on the environment—not to mention ideal for those who are lactose intolerant (raises hand) or vegan—many of them are still not cheesy enough. Now, a team of scientists from the University of Copenhagen in Denmark has created nondairy cheese with a taste and texture that’s much closer to the real thing. Instead of developing some sort of futuristic technology, they harnessed the transformative power of a process that has been used to make traditional cheese for thousands of years— fermentation .

Just add bacteria

Why are plant-based cheeses so notoriously difficult to make? Not all proteins are created equal. Because plant proteins behave so differently from milk proteins, manufacturers rely on coconut oil, starch, or gums as hardening agents and then add colors and flavors that give the finished product some semblance of cheese.

Enlarge / A premature baby in the neonatal intensive care unit at University of Iowa Stead Family Children's Hospital in Iowa City, Iowa on August 13, 2021. The baby was born two days earlier at 22 weeks and at birth weighed just 1 lb., 0.1 oz. (credit: Getty | Michael S. Williamson/The Washington Post )

The Food and Drug Administration is warning health care providers not to use probiotics containing live bacteria or yeast in preterm infants after the agency began investigating the July death of a preterm, low-weight infant given such a product in an unnamed hospital.

The infant developed sepsis from the bacterium in the probiotic product—Evivo with MCT Oil made by Infinant Health—and subsequently died.

In a statement to Ars, the FDA said it quickly investigated the death after receiving an initial report on July 31. "Infant deaths are especially tragic and determining causality of preterm infant death can be particularly complicated," an agency spokesperson said. The agency reviewed medical records and laboratory tests from the case and collected clinical samples and product samples for analysis.

Enlarge / Competitors take part in "Tough Mudder" at the Glen Helen Raceway in San Bernardino, California, United States on April 2, 2023. (credit: Getty | Tayfun CoÅkun )

Hundreds of people who participated in a recent Tough Mudder event—a very muddy obstacle course race—held in Sonoma, California, have fallen ill with pustular rashes, lesions, fever, flu-like symptoms, nerve pain, and other symptoms, local health officials and media outlets report.

The cases could be caused by various infectious agents, including Staphylococcus bacteria, but the leading culprit is the relatively obscure Aeromonas bacteria— specifically A. hydrophila , according to the Sonoma County health department. In a statewide alert this week, the California Department of Public Health said it is considering it an Aeromonas outbreak, noting that multiple wound cultures have yielded the hardy bacterium.

A spokesperson for the Sonoma County health department told the Los Angeles Times on Thursday that, based on calls and emails the department had received, health officials estimate that the outbreak involves around 300 cases . Tough Mudder participants, meanwhile, have tallied as many as 489 cases in online forums.

Enlarge / An armadillo prepares to cross a gravel road as the space shuttle Endeavour rests on the launch pad at Kennedy Space Center before the scheduled launch of STS-130 in Cape Canaveral, Florida, February 4, 2010. (credit: Getty | JIM WATSON )

A Florida man's unexplained case of leprosy last year adds to mounting evidence that the rare and often misunderstood bacterial infection has become endemic to the central part of the Sunshine State—and that it may, in fact, lurk in the environment there, possibly in the soil.

In a research letter appearing in the August issue of Emerging Infectious Diseases, three dermatologists detailed the man's case and their concerns for local transmission. They note that the 54-year-old man, like several others in the state who contracted the disease, reported no established risk factors that might explain their infection. He hadn't traveled abroad, where he could have picked up the infection, or had any exposure to armadillos, which live in Florida and naturally carry the bacteria that cause leprosy. He also didn't have any prolonged contact with people from leprosy-endemic countries or connections to anyone known to have leprosy.

But he did spend a lot of time outdoors; he worked as a landscaper. In fact, many of the recent Florida cases lacked traditional risk factors but reported spending a lot of time outdoors. The similarity "supports the investigation into environmental reservoirs as a potential source of transmission," the doctors wrote.

Enlarge / Ukrainian medics of the battalion "Da Vinci Wolves" and "Ulf" paramedical unit transfer a wounded Ukrainian soldier to a stabilization point on the Bakhmut front as the Russia-Ukraine war continues on April 6, 2023. (credit: Getty | Diego Herrera Carcedo/Anadolu Agency )

Russia's invasion of Ukraine is fueling a dangerous rise in bacterial drug resistance—an alarming reality made clear by a recent case report of an injured Ukrainian soldier who became infected with six different extensively drug-resistant bacteria, one of which was resistant to every antibiotic tested.

Health experts are sounding the alarm that the nearly unbeatable germs will likely spread beyond the war-torn country's borders. "Given the forced migration of the population, multidrug resistance of wound pathogens is now a problem not only for Ukraine but also for healthcare systems around the world, especially in the EU," Ukrainian scientists and doctors wrote in a recent letter in the Irish Journal of Medical Scientists.

The rise of antibiotic resistance is a long-standing, critical threat to global public health. In 2019, antimicrobial resistance was directly responsible for an estimated 1.27 million deaths worldwide and linked to an estimated 4.95 million total, according to an analysis published last year in the Lancet .