Exclusive: Tactics include proposals to raise smoking age to avoid outright ban, and exemptions for cigars, says Cancer Research UK chief

Tobacco firms are lobbying MPs and peers in an effort to derail Rishi Sunak’s flagship policy to phase out smoking, the head of Britain’s biggest cancer charity has said.

The prime minister’s landmark legislation – which would bar anyone born after 2009 from buying cigarettes and make England the first country in the world to ban smoking – is due to be debated in parliament for the first time on Tuesday.

Groundbreaking research finds dropping the third stage of standard MRI test for the disease doesn’t hamper detection rates, and cuts costs in half

Cutting the duration of MRI scans for prostate cancer by a third would make them cheaper and more accessible without reducing their accuracy. That is the key result of a UK trial which indicates that lowering costs could ensure more men are offered scans.

According to Cancer Research UK, there are about 52,300 new prostate cancer cases every year in the UK, equal to more than 140 a day.

Largest study of its kind predicts 85% increase in deaths from the disease in same period as more men live longer

The number of men diagnosed with prostate cancer worldwide is projected to double to 2.9 million a year by 2040, with annual deaths predicted to rise by 85%, according to the largest study of its kind.

Prostate cancer is already a major cause of death and disability, and the most common form of male cancer in more than 100 countries. But with populations ageing and life expectancy rising globally, a new analysis forecasts a dramatic surge in cases and deaths over the next 15 years.

A new study suggests coffee could prevent bowel cancer reoccurring – but claims for its healing properties have abounded since the 15th century

Last week a study was published showing that people with bowel cancer who drink coffee – quite a lot of coffee, two to four cups a day – were less likely to suffer a return of the disease. Experts have said that if the results hold in further studies, coffee could be prescribed to cancer patients on the NHS. That coffee does have an effect on human function is beyond dispute – but whether that impact is beneficial or detrimental has been the subject of contention since Sufi mystics began consuming the beverage some time in the mid-15th century.

The Indigenous peoples of the forests of Kaffa in south-west Ethiopia foraged berries from wild coffee plants that were shipped across the Red Sea to prepare the decoction known as qahwa, which Yemeni Sufis incorporated into their night-time religious ceremonies to reduce their desire for sleep. Once mainstream Islamic courts ruled coffee was not intoxicating, consumption became widespread among the Muslim populations in the Middle East and the Ottoman empire.

Cannabis is not a treatment, let alone a cure for cancer. It is not a substitute for chemotherapy and can cause significant side effects

It’s fair to say my patients were using cannabis long before I knew it was a “thing”.

My first memory of encountering the drug was a decade ago at the bedside of a dying patient. I was about to commence a morphine infusion when a burly man quietly asked me to step outside. Moments later, my apprehension turned to surprise when, tears streaming down his face, the son begged me to wait while his brother procured some cannabis from an underground supplier, “just in case it works”.

Tests that can identify early changes in cells would give doctors more time to offer treatment, say Cambridge researchers

Scientists at a recently opened cancer institute at Cambridge University have begun work that is pinpointing changes in cells many years before they develop into tumours. The research should help design radically new ways to treat cancer, they say.

The Early Cancer Institute – which has just received £11m from an anonymous donor – is focused on finding ways to tackle tumours before they produce symptoms. The research will exploit recent discoveries which have shown that many people develop precancerous conditions that lie in abeyance for long periods.

Enlarge (credit: Martin Barraud )

When we talk about memories in biology, we tend to focus on the brain and the storage of information in neurons. But there are lots of other memories that persist within our cells. Cells remember their developmental history, whether they've been exposed to pathogens, and so on. And that raises a question that has been challenging to answer: How does something as fundamental as a cell hold on to information across multiple divisions?

There's no one answer, and the details are really difficult to work out in many cases. But scientists have now worked out one memory system in detail. Cells are able to remember when their parent had a difficult time dividing—a problem that's often associated with DNA damage and cancer. And, if the problems are substantial enough, the two cells that result from a division will stop dividing themselves.

Setting a timer

In multicellular organisms, cell division is very carefully regulated. Uncontrolled division is the hallmark of cancers. But problems with the individual segments of division—things like copying DNA, repairing any damage, making sure each daughter cell gets the right number of chromosomes—can lead to mutations. So, the cell division process includes lots of checkpoints where the cell makes sure everything has worked properly.

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Bill being laid before Scottish parliament could, if approved, allow people in Britain to take their own lives within the law

UK membership of Dignitas, the Swiss assisted dying association, has jumped to 1,900 people – a 24% rise during 2023 – as an assisted dying bill is laid before the Scottish parliament.

People from the UK now make up the second largest group who have signed up to the organisation, which is based near Zurich and helps people take their own lives. The largest group is currently Germans, although they can now get help to end their lives at home after a 2020 court ruling .

On 28 March it is the 60th anniversary of the discovery of Epstein-Barr virus, the most common viral infection in humans. The virus was first discovered in association with a rare type of cancer located in Africa, but is now understood to be implicated in 1% of cancers, as well as the autoimmune disease multiple sclerosis, among others. Ian Sample meets Lawrence Young, professor of molecular oncology at Warwick Medical School, to hear the story of this virus, and how understanding it might help us prevent and treat cancer and other illnesses.

Read an obituary of Sir Anthony Epstein, who died in February 2024