Enlarge / A photo of Braarudosphaera bigelowii with the nitroplast indicated by an arrowhead. (credit: Tyler Coale )

The complex cells that underlie animals and plants have a large collection of what are called organelles—compartments surrounded by membranes that perform specialized functions. Two of these were formed through a process called endosymbiosis, in which a once free-living organism is incorporated into a cell. These are the mitochondrion, where a former bacteria now handles the task of converting chemical energy into useful forms, and the chloroplast, where photosynthesis happens.

The fact that there are only a few cases of organelles that evolved through endosymbiosis suggests that it's an extremely rare event. Yet researchers may have found a new case, in which an organelle devoted to fixing nitrogen from the atmosphere is in the process of evolving. The resulting organelle, termed a nitroplast, is still in the process of specialization.

Getting nitrogen

Nitrogen is one of the elements central to life. Every DNA base, every amino acid in a protein contains at least one, and often several, nitrogen atoms. But nitrogen is remarkably difficult for life to get ahold of. N ₂ molecules might be extremely abundant in our atmosphere, but they're extremely difficult to break apart. The enzymes that can, called nitrogenases, are only found in bacteria, and they don't work in the presence of oxygen. Other organisms have to get nitrogen from their environment, which is one of the reasons we use so much energy to supply nitrogen fertilizers to many crops.

Enlarge / The plague bacteria, Yersina pestis , is a close relative of the toxin-producing species studied here. (credit: Callista Images )

Life-forms with no brain are capable of some astounding things. It might sound like sci-fi nightmare fuel, but some bacteria can wage kamikaze chemical warfare.

Pathogenic bacteria make us sick by secreting toxins. While the release of smaller toxin molecules is well understood, methods of releasing larger toxin molecules have mostly eluded us until now. Researcher Stefan Raunser, director of the Max Planck Institute of Molecular Physiology, and his team finally found out how the insect pathogen Yersinia entomophaga (which attacks beetles) releases its large-molecule toxin.

They found that designated “soldier cells” sacrifice themselves and explode to deploy the poison inside their victim. “YenTc appears to be the first example of an anti-eukaryotic toxin using this newly established type of secretion system,” the researchers said in a study recently published in Nature.

Enlarge (credit: Weber )

What if human blood turned into a sort of rubbery slime that can bounce back into a wound and stop it from bleeding in record time?

Until now, it was a mystery how hemolymph, or insect blood, was able to clot so quickly outside the body. Researchers from Clemson University have finally figured out how this works through observing caterpillars and cockroaches. By changing its physical properties, the blood of these animals can seal wounds in about a minute because the watery hemolymph that initially bleeds out turns into a viscoelastic substance outside of the body and retracts back to the wound.

“In insects vulnerable to dehydration, the mechanistic reaction of blood after wounding is rapid,” the research team said in a study recently published in Frontiers in Soft Matter. “It allows insects to minimize blood loss by sealing the wound and forming primary clots that provide scaffolding for the formation of new tissue.”

Enlarge / Active geology could have helped purify key chemicals needed for life. (credit: Christof B. Mast)

In some ways, the origin of life is looking much less mystifying than it was a few decades ago. Researchers have figured out how some of the fundamental molecules needed for life can form via reactions that start with extremely simple chemicals that were likely to have been present on the early Earth. (We've covered at least one of many examples of this sort of work.)

But that research has led to somewhat subtler but no less challenging questions. While these reactions will form key components of DNA and protein, those are often just one part of a complicated mix of reaction products. And often, to get something truly biologically relevant, they'll have to react with some other molecules, each of which is part of its own complicated mix of reaction products. By the time these are all brought together, the key molecules may only represent a tiny fraction of the total list of chemicals present.

So, forming a more life-like chemistry still seems like a challenge. But a group of German chemists is now suggesting that the Earth itself provides a solution. Warm fluids moving through tiny fissures in rocks can potentially separate out mixes of chemicals, enriching some individual chemicals by three orders of magnitude.

Enlarge (credit: Design Cells )

When we catch a whiff of perfume or indulge in a scented candle, we are smelling much more than Floral Fantasy or Lavender Vanilla. We are actually detecting odor molecules that enter our nose and interact with cells that send signals to be processed by our brain. While certain smells feel like they’re unchanging, the complexity of this system means that large odorant molecules are perceived as the sum of their parts—and we are capable of perceiving the exact same molecule as a different smell.

Smell is more complex than we might think. It doesn’t consist of simply detecting specific molecules. Researcher Wen Zhou and his team from the Institute of Psychology of the Chinese Academy of Sciences have now found that parts of our brains analyze smaller parts of the odor molecules that make things smell.

Smells like…

So how do we smell? Odor molecules that enter our noses stimulate olfactory sensory neurons . They do this by binding to odorant receptors on these neurons (each of which makes only one of approximately 500 different odor receptors). Smelling something activates different neurons depending on what the molecules in that smell are and which receptors they interact with. The sensory neurons in the piriform cortex of the brain then use the information from the sensory neurons and interpret it as a message that makes us smell vanilla. Or a bouquet of flowers. Or whatever else.

Enlarge / Trying out the robot on a glacier. (credit: NASA/JPL-Caltech )

Icy ocean worlds like Europa or Enceladus are some of the most promising locations for finding extra-terrestrial life in the Solar System because they host liquid water. But to determine if there is something lurking in their alien oceans, we need to get past ice cover that can be dozens of kilometers thick. Any robots we send through the ice would have to do most of the job on their own because communication with these moons takes as much as 155 minutes.

Researchers working on NASA/JPL’s technology development project called Exobiology Extant Life Surveyor (EELS) might have a solution to both those problems. It involves using an AI-guided space snake robot. And they actually built one.

Geysers on Enceladus

The most popular idea to get through the ice sheet on Enceladus or Europa so far has been thermal drilling, a technique used for researching glaciers on Earth. It involves a hot drill that simply melts its way through the ice. “Lots of people work on different thermal drilling approaches, but they all have a challenge of sediment accumulation, which impacts the amount of energy needed to make significant progress through the ice sheet,” says Matthew Glinder, the hardware lead of the EELS project.